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RESEARCH FELLOW
DescriptionThe research project is focused for "targeting Cdc42 to rejuvenate aged hematopoietic and intestinal stem cells". The objective is to demonstrate that CASIN and related small molecules targeting Cdc42 show selective activity toward Cdc42 in murine and human hematopoietic and intestinal stem/progenitor cells, can restore a youthful polarity and epigenetic clock, and improve engraftment potential.Cincinnati Children's Research and Training at a Glance: Among the top in NIH funding for pediatric research institutions Over 1.4 million square feet of research laboratory space 900+ scientists conducting basic, translational, and clinical research Over 2000 publications annually in top-tier journals
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